2021-2022 Varsity Football
| Date | | Opponent | Location | Result | | W/L |
|---|
| Fri, Aug 27
| | Palo Duro | Seminole | 26-34 | | L |
| Palo Duro | Seminole |
| Fri, Sep 03
| | Shallowater | Shallowater | 23-36 | | L |
| Shallowater | Shallowater |
| Fri, Sep 10
| | Denver City | Seminole | 22-18 | | W |
| Denver City | Seminole |
| Fri, Sep 17
| | Andrews | Andrews | 17-63 | | L |
| Andrews | Andrews |
| Fri, Sep 24
| | Muleshoe | Seminole | 51-35 | | W |
| Muleshoe | Seminole |
| Fri, Oct 01
| | Monahans | Seminole | 21-34 | | L |
| Monahans | Seminole |
| Fri, Oct 08
| | Estacado (district) | Seminole | 10-20 | | L |
| Estacado (district) | Seminole |
| Fri, Oct 22
| | Borger (district) | Borger | 27-0 | | W |
| Borger (district) | Borger |
| Fri, Oct 29
| 7 p.m. | Perryton (district) | Seminole | | | |
| Perryton (district) | Seminole |
| Fri, Nov 05
| 7 p.m. | Levelland (district) | Levelland | | | |
| Levelland (district) | Levelland |
