| Sat, Nov 07
| | Permian | Seminole | 63-37 | | W |
| Permian | Seminole |
| Tue, Nov 10
| | Vega | LCU | 58-25 | | W |
| Vega | LCU |
| Fri, Nov 13
| 4:30 p.m. | Odessa high CANCELLED | Odessa | | | |
| Odessa high CANCELLED | Odessa |
| Tue, Nov 17
| | Estacado | Seminole | 54-31 | | W |
| Estacado | Seminole |
| Fri, Nov 20
| | New Home | New Home | 45-32 | | W |
| New Home | New Home |
| Mon, Nov 23
| 11:00 | San Angelo Central CANCELL | San Angelo | | | |
| San Angelo Central CANCELL | San Angelo |
| Tue, Dec 01
| | Plainview | Plainview | 21-44 | | L |
| Plainview | Plainview |
| Fri, Dec 04
| | Coronado | Seminole | 74-15 | | W |
| Coronado | Seminole |
| Tue, Dec 08
| | Midland Lee | Midland | 41-22 | | W |
| Midland Lee | Midland |
| Tue, Dec 15
| | Lubbock Christian | Seminole | 60-30 | | W |
| Lubbock Christian | Seminole |
| Fri, Dec 18
| | Cooper | Seminole | 33-42 | | L |
| Cooper | Seminole |
| Sat, Dec 19
| | Monterey | Seminole | 62-18 | | W |
| Monterey | Seminole |
| Mon, Dec 21
| | Sudan | Seminole | 65-35 | | W |
| Sudan | Seminole |
| Tue, Dec 29
| | Crane | Crane | 86-11 | | W |
| Crane | Crane |
| Thu, Dec 31
| | Lubbock High | Lubbock | 57-36 | | W |
| Lubbock High | Lubbock |
| Sat, Jan 02
| | Denver City | Denver City | 64-8 | | W |
| Denver City | Denver City |
| Tue, Jan 05
| 4:30 p.m. | Pecos (District) CANCELLED | Seminole | | | |
| Pecos (District) CANCELLED | Seminole |
| Fri, Jan 08
| | Fort Stockton (District) | Seminole | 79-11 | | W |
| Fort Stockton (District) | Seminole |
| Tue, Jan 12
| | Andrews (District) | Andrews | 47-28 | | W |
| Andrews (District) | Andrews |
| Fri, Jan 15
| 4:30 p.m. | Monahans (District) | Seminole | | | |
| Monahans (District) | Seminole |
| Tue, Jan 19
| 4:30 p.m. | Greenwood (District) | Greenwood | | | |
| Greenwood (District) | Greenwood |
| Fri, Jan 22
| 4:30 p.m. | Pecos (District) | Pecos | | | |
| Pecos (District) | Pecos |
| Tue, Jan 26
| 4:30 p.m. | Fort Stockton (District) | Fort Stockton | | | |
| Fort Stockton (District) | Fort Stockton |
| Tue, Feb 02
| 4:30 p.m. | Andrews (District) | Andrews | | | |
| Andrews (District) | Andrews |
| Fri, Feb 05
| 4:30 p.m. | Greenwood (District) | Seminole | | | |
| Greenwood (District) | Seminole |
