2020-2021 Varsity W. Basketball
| Date | | Opponent | Location | Result | | W/L |
|---|
| Sat, Nov 07
| 1:30 p.m. | Permian | Seminole | | | |
| Permian | Seminole |
| Sat, Nov 07
| 1:30 | Permian | Seminole | | | |
| Permian | Seminole |
| Tue, Nov 10
| 6:30 p.m. | Vega | LCU | | | |
| Vega | LCU |
| Fri, Nov 13
| 6:00 P.m. | Odessa High | Odessa | | | |
| Odessa High | Odessa |
| Sat, Nov 14
| 12:15 | Midland Christian | Seminole | | | |
| Midland Christian | Seminole |
| Sat, Nov 14
| 11:00 | Midland Christian | Seminole | | | |
| Midland Christian | Seminole |
| Tue, Nov 17
| 6:30 p.m. | Estacado | Seminole | | | |
| Estacado | Seminole |
| Fri, Nov 20
| 6:30 p.m. | New Home | New Home | | | |
| New Home | New Home |
| Mon, Nov 23
| 12:15 | San Angelo Central | San Angelo | | | |
| San Angelo Central | San Angelo |
| Fri, Dec 04
| 6:00 P.m. | Coronado | Seminole | | | |
| Coronado | Seminole |
| Tue, Dec 08
| 6:00 P.m. | Midland Lee | Midland | | | |
| Midland Lee | Midland |
| Tue, Dec 15
| 6:30 p.m. | Lubbock Christian | Seminole | | | |
| Lubbock Christian | Seminole |
| Fri, Dec 18
| 2:30 P.m. | Cooper | Seminole | | | |
| Cooper | Seminole |
| Sat, Dec 19
| 3:30 p.m. | Monterey | Seminole | | | |
| Monterey | Seminole |
| Mon, Dec 21
| 2:15 p.m. | Sudan | Seminole | | | |
| Sudan | Seminole |
| Tue, Dec 29
| 2:30 P.m. | Crane | Crane | | | |
| Crane | Crane |
| Tue, Dec 29
| 6:00 P.m. | Andrews (District) | Seminole | | | |
| Andrews (District) | Seminole |
| Thu, Dec 31
| 11:30 | Lubbock High | Lubbock | | | |
| Lubbock High | Lubbock |
| Sat, Jan 02
| 1:30 | Denver City | Denver City | | | |
| Denver City | Denver City |
| Tue, Jan 05
| 6:00 P.m. | Pecos (District) | Seminole | | | |
| Pecos (District) | Seminole |
| Tue, Jan 05
| 6:00 P.m. | Greenwood (District) | Seminole | | | |
| Greenwood (District) | Seminole |
| Fri, Jan 08
| 6:00 P.m. | Fort Stockton (District) | Seminole | | | |
| Fort Stockton (District) | Seminole |
| Tue, Jan 12
| 6:00 P.m. | Andrews (District) | Andrews | | | |
| Andrews (District) | Andrews |
| Fri, Jan 15
| 6:00 P.m. | Monahans | Seminole | | | |
| Monahans | Seminole |
| Tue, Jan 19
| 6:00 P.m. | Greenwood | Greenwood | | | |
| Greenwood | Greenwood |
| Fri, Jan 22
| 6:00 P.m. | Pecos (District) | Pecos | | | |
| Pecos (District) | Pecos |
| Tue, Jan 26
| 6:00 P.m. | Fort Stockton (District) | Fort Stockton | | | |
| Fort Stockton (District) | Fort Stockton |
| Tue, Feb 02
| 6:00 P.m. | Monahans (District) | Monahans | | | |
| Monahans (District) | Monahans |
